Moreover, our data obtained from OSMI-1 and Thiamet-G treated murine osteoclast precursors both showed distinct, but highly significant association patterns with considerable enrichment scores for genes deregulated in human macrophages obtained from synovial fluid of inflamed joints from patients with RA (Fig.
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Dynamic changes in O-GlcNAcylation regulate osteoclast differentiation and bone loss via nucleoporin 153.
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