Differential Regulation of CD45 Expression on Granulocytes, Lymphocytes, and Monocytes in COVID-19.

J Clin Med · 2022 · PMC9318847 · PMID 35887979

Europe PMC DOI

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0.0012

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0.0012

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highly significantp = 0.0012actually significant

Incubation of whole blood samples from healthy volunteers with LPS revealed a marked 4.3-fold increase in CD45 expression on endotoxin-stimulated granulocytes from 26,898 ± 2985 to 114,144 ± 5293 ( p < 0.0001), and a gradual, but highly significant, increase on lymphocytes from 119,202 ± 8970 to 158,107 ± 6564 ( p = 0.0012) and monocytes from 209,266 ± 15,953 to 284,693 ± 11,880 ( p = 0.0005).

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