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Digoxin use and outcomes after myocardial infarction in patients with atrial fibrillation.

Basic Clin Pharmacol Toxicol · 2022 · PMC9321089 · PMID 35420260

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a decreasing trendno p-value reported
Concurrently, recent data from the United States show a decreasing trend in digoxin toxicity and adverse outcomes. 32 Thus, the observed neutral association between initial digoxin dosage and clinical outcomes likely reflects an awareness of patient‐specific factors, such as kidney function and age, that affect SDC and improved monitoring rather than biological effects.

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