Historical exposure to chemicals reduces tolerance to novel chemical stress in Daphnia (waterflea).

Mol Ecol · 2022 · PMC9321109 · PMID 35377519

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an overall trendno p-value reported

TGP effects visualized through PTA plots revealed an overall trend of lower mortality and smaller fitness change across clonal generations in naïve than in experienced genotypes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.