Multi-omics analysis identifies a CYP9K1 haplotype conferring pyrethroid resistance in the malaria vector Anopheles funestus in East Africa.

Mol Ecol · 2022 · PMC9321817 · PMID 35546741

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp = 1.7 × 10 −5actually significant

3.2.4 Cameroon For SNPs present in three or more mosquitoes, the most highly significant SNP was in the cytochrome P450 CYP304B1 on chromosome 2 ( p = 1.7 × 10 −5 ).

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markedly significantno p-value reported

However, when comparing field resistant mosquitoes to laboratory susceptible, the pyrethroid resistance locus rp1 and SNPs around the ABC transporter ABCG4 were consistently significant, except for Uganda where SNPs in the P450 CYP9K1 was markedly significant.

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