Discordant prognosis of mismatch repair deficiency in colorectal and endometrial cancer reflects variation in antitumour immune response and immune escape.

As expected, dMMR was associated with a substantial and highly significant improvement in DFS in CRC (HR RE = 0.62; 95% CI = 0.55–0.70%; p < 1e‐04), with moderate heterogeneity across studies (I2 = 47%, τ2 = 0.015, p = 0.036) (Figure 1 ).

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