Genetic Biomarkers as Predictors of Response to Tocilizumab in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.

Genes (Basel) · 2022 · PMC9323282 · PMID 35886067

Europe PMC DOI

hedged sentence

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closest p · 1.0× alpha

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boldest claim

The sentences

borderline significancep = 0.05actually significant

Furthermore, the AAC haplotype for rs12083537, rs2228145 and rs4329505 of IL6R was strongly associated with a poorer response to TCZ based on the swollen joint count ( p = 0.00004) and with borderline significance of the EULAR response ( p = 0.05).

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