Exposure-Response Modeling and Simulation to Support Human Dosing of Botulism Antitoxin Heptavalent Product.

Clin Pharmacol Ther · 2022 · PMC9323444 · PMID 35467014

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highly significantno p-value reported

For serotype A neurotoxin, where there were the most data available, the AUC effect on survival was highly significant, suggesting a direct relationship between BAT product levels and the probability of survival in GPs and NHPs.

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