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C-reactive protein trajectories and the risk of all cancer types: A prospective cohort study.

Int J Cancer · 2022 · PMC9325055 · PMID 35368093

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a decreasing trendno p-value reported
A total of 43 258 participants (82.75%) who consistently maintained a low CRP concentration (mean CRP concentrations ranged from 1.00 mg/L in 2006 to 1.30 mg/L in 2010) were referred to as the low‐stable pattern; 2591 participants (4.96%) who initially had moderate CRP levels and then experienced an increase of CRP (mean FBG concentrations ranged from 2.49 mg/L in 2006 to 8.96 mg/L in 2010) were referred to as the moderate‐increasing pattern; 2068 (3.96%) participants who initially had increasing CRP concentrations and then experienced a decreasing trend (mean CRP concentrations ranged from 2.37 mg/L in 2006 to 9.43 mg/L in 2008 and 2.92 mg/L in 2010) were referred to as the increasing‐decreasing pattern; 4359 (8.34%) participants who initially had elevated concentrations of CRP but consistently decreased (mean CRP concentrations ranged from 8.56 mg/L in 2006 to 2.54 mg/L in 2010) were referred as to the elevated‐decreasing pattern. 3.2 Baseline characteristics of the study population A total of 52 276 participants (39 691 men and 12 585 women) were included in the current study, the mean age was 49.29 ± 11.80 years.

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