Association of antioxidant nutraceuticals and acetaminophen (paracetamol): Friend or foe?

J Food Drug Anal · 2018 · PMC9326882 · PMID 29703389

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

near to significancep = 0.09so close (0.05 < p ≤ 0.1)

All urinary pharmacokinetic parameters of unchanged APAP (Sul-APAP, Cys-APAP and Mer-APAP) did not differ between treatment and placebo groups, whereas the decrease in urinary T max and the increase in urinary AUC of Glu-APAP were near to significance (p = 0.09 and p = 0.06) [ 44 ].

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near significanceno p-value reported

Urinary Sul-APAP and Mer-APAP, but not Glu-APAP were higher after 4 weeks of supplementation, when compared to week 0 and urine levels of unchanged APAP increased by 18% (near significance) [ 42 ].

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