<i>Arisaema heterophyllum Blume</i> Monomer Stigmasterol Targets PPAR<i>γ</i> and Inhibits the Viability and Tumorigenicity of Lung Adenocarcinoma Cells NCI-H1975.

Evid Based Complement Alternat Med · 2022 · PMC9328949 · PMID 35911149

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an increasing trendno p-value reported

The expression levels of cell cyclins cyclinD1, CDK2, CDK4, and CDK6 were detected using qPCR and western blot assays, implying that stigmasterol could reduce the mRNA and protein expression of cyclinD1, CDK2, CDK4, and CDK6, whereas in the stigmasterol + GW9662 co-treatment group, the mRNA and protein expressions of cyclinD1, CDK2, CDK4, and CDK6 presented an increasing trend (Figures 5(g) and 5(h) ). 4.

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