Risk of Developing Non-Cancerous Central Nervous System Diseases Due to Ionizing Radiation Exposure during Adulthood: Systematic Review and Meta-Analyses.

mound workers potentially exposed to external or internal (polonium-210, plutonium isotopes, or tritium) radiation (mean dose from external radiation: 26.1 mSv; max: 939.1 mSv; mean lung dose from external and internal radiation combined: 100.1 mSv; max: 17.5 Sv; mean liver dose from external and internal radiation: 34.6 mSv; max: 2.3 Sv), the mortality due to diseases of the nervous system was not different from that of the general population, regardless of the radiation status of the workers or the type of radionuclides for those with intakes, but a positive trend was suggested as SMRs increased with increasing categories of occupational cumulative dose primarily due to photons ( p = 0.03) [ 42 ].

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(2021) reported among the whole cohort a non-significant SMR for nervous system diseases compared with national rates based on 815 deaths, but a borderline significant increase in mortality due to Parkinson’s disease was observed (SMR = 1.16; 95% CI: 1.00, 1.34; n deaths = 193), and a positive dose–response relationship was suggested (ERR at 100 mGy = 0.16; 95% CI: −0.07, 0.40; n deaths = 273) [ 33 ].

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