Long-Term Persistence of Mitochondrial DNA Instability in HIV-Exposed Uninfected Children during and after Exposure to Antiretroviral Drugs and HIV.

Moreover, though not quite statistically significant, it is of note that, among children who had an elevated heteroplasmy rate at birth, ALT concentration increased with longer exposure to maternal ARV, while it was almost null among children whose heteroplasmy rate at birth was ≤1% ( p for interaction = 0.070; Table 6 ).

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