Assuming a normal distribution, and have applied a simple T-test, which showed that the difference is highly significant. – In Figure 4B the authors state "At the phylum level the patterns were more prominent in Proteobacteria, containing more N6mdA than 5mdC, while a reverse trend of more 5mdC than N6mdA was observed for Bacteroidetes and Firmicutes".
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Global analysis of cytosine and adenine DNA modifications across the tree of life.
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