SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model.

Nat Commun · 2022 · PMC9338273 · PMID 35906230

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highly significantno p-value reported

Whereas lung titer reductions in treated males were highly significant compared to vehicle-treated males, females, or all vehicle-treated animals combined, no significant change in lung virus load against any of these vehicle groups was detected in females treated with molnupiravir.

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