Post-neoadjuvant assessment of tumour budding according to ITBCC subgroups delivers stage- and regression-grade independent prognostic information in intestinal-type gastric adenocarcinoma.

J Pathol Clin Res · 2022 · PMC9353660 · PMID 35715937

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highly significantno p-value reported

Multivariable survival analysis In a multivariable survival analysis (Cox regression model) including age (continuous variable), sex, resection status (R0 versus R1), UICC stage (I–IV), and tumour regression grading (TRG1b, TRG2, TRG3), the ITBCC TB subgroups (Bd1 versus Bd2 versus Bd3 [ p < 0.001]) and UICC stage ( p = 0.005) proved to be independent, highly significant survival parameters.

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