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Development, <i>In-Vitro</i> Characterization and <i>In-Vivo</i> Osteoinductive Efficacy of a Novel Biomimetically-Precipitated Nanocrystalline Calcium Phosphate With Internally-Incorporated Bone Morphogenetic Protein-2.

Front Bioeng Biotechnol · 2022 · PMC9354744 · PMID 35935495

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an increasing trendno p-value reported
Quantitative analysis ( Figure 8B ) showed an increasing trend of volume density of newly formed bone ( Figure 8B1 ) with the increase of incorporated BMP-2 amount.

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a decreasing trendno p-value reported
The volume density of FGBCs ( Figure 8B4 ) showed a decreasing trend with the increase of BMP-2 incorporation amount with the lowest value detected in the group of BpNcCaP+50 μg BMP-2. 4 Discussion Most of the clinically available bone-defect-filling materials lack proper degradability and efficient osteoinductivity ( Bhat et al., 2021 ).

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