Daratumumab, a monoclonal antibody against the CD38 protein expressed on the clonal plasma cells, was associated with a shorter time to first hematologic and deep response as well as a highly significant improvement in cardiac and renal response in the ANDROMEDA trial either alone or in combination with CyBorD [ 10 – 12 ].
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Blood Cancer and the Heart: Light Chain Cardiomyopathy in Refractory Multiple Myeloma.
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