Integrative Genomic Profiling Uncovers Therapeutic Targets of Acral Melanoma in Asian Populations.

Clin Cancer Res · 2022 · PMC9359751 · PMID 35294533

Europe PMC DOI

hedged sentences

0.0680

closest p · 1.4× alpha

0.0900

boldest claim

The sentences

borderline significanceP = 0.068so close (0.05 < p ≤ 0.1)

24.4%) with borderline significance ( P = 0.068).

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marginal significanceP = 0.09so close (0.05 < p ≤ 0.1)

As a result, in the comparison between Signature 3 + acral melanoma lesions and other lesions, no significant difference was observed in numbers of HRD-LOH events ( P = 0.78), TAI ( P = 0.49), and LST ( P = 0.12), while Signature 3 + lesions tended to have higher HRD-sum values with marginal significance (Mann–Whitney U test, P = 0.09; Fig. 2B ).

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