MYC sensitises cells to apoptosis by driving energetic demand.

Nat Commun · 2022 · PMC9363429 · PMID 35945217

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highly significantP value = 2.2 × 10 −16actually significant

Withdrawal of glutamine reduced global translation in both conditions, but there was a highly significant increase in translation driven by MYC compared to that seen in cells transduced with the pM6P vector in the absence of glutamine ( P value = 2.2 × 10 −16 ).

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