an increasing trendp = 0.120
The proportion of morning stiffness ( p = 0.015), joint deformity ( p = 0.015), and interstitial lung disease (ILD) ( p = 0.001) in ACPA + RA patients was significantly higher than in ACPA - RA patients, and disease activity score using 28 joint counts (DAS28)-ESR (3) also showed an increasing trend ( p = 0.120).