Immunomodulatory treatment of interstitial lung disease.

Ther Adv Respir Dis · 2022 · PMC9364223 · PMID 35938712

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

a trend towards significancep = 0.08so close (0.05 < p ≤ 0.1)

11 The multicenter, randomized FAST trial explored the effect of low-dose prednisone and intravenous (iv) CYC for 6 months, followed by maintenance AZA in SSc-ILD. Compared with placebo, predicted FVC in the treatment group improved by 4.2%, but only with a trend towards significance ( p = 0.08) after 12 months. 17 Due to potential bladder toxicity, continuing CYC long-term is challenging.

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