The most significant decrease in NE levels was observed in patients with severe disease and good prognosis (2.5-fold on day 1, 1.1-fold on day 3 and 0.2-fold on day 5 compared to healthy controls, P = 0.012), while those with mild disease but poor prognosis showed an increasing trend in NE levels (1.2-fold on day 1, 1.5-fold on day 3 and 2.9-fold on day 5 compared to healthy controls).
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Longitudinal changes in the hypothalamic-pituitary-adrenal axis and sympathetic nervous system are related to the prognosis of stroke.
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