Association between eight hypermethylation-related genes and gastric cancer: a systematic review and meta-analysis.

Transl Cancer Res · 2022 · PMC9372225 · PMID 35966315

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an increasing trendno p-value reported

The risk of methylation of the p16 , CDH1 , hMLH1 , RUNX3 and DAPK genes showed an increasing trend in the regular group—precancerous tissue—cancer tissue. p16 , CDH1 , hMLH1 , RUNX3 and RASSF1A methylation had no statistical significance between precancerous lesions and normal tissues.

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