Small Fiber Density At the study end, intraepidermal nerve fiber (IENF) density in plantar footskin showed a mild trend to reduction in ZDF rats (control: 28.3 ± 2.6, ZDF: 25.4 ± 1.3 IENF/mm) that was not impacted by NSI-189 treatment (ZDF+NSI-189: 24.25 ± 1.8 IENF/mm).
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Enhancement of Mitochondrial Function by the Neurogenic Molecule NSI-189 Accompanies Reversal of Peripheral Neuropathy and Memory Impairment in a Rat Model of Type 2 Diabetes.
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