Reverse Translating Molecular Determinants of Anti-Programmed Death 1 Immunotherapy Response in Mouse Syngeneic Tumor Models.

Mol Cancer Ther · 2022 · PMC9377732 · PMID 34965960

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a positive trendno p-value reported

Moreover, murine-GEP score showed a positive trend at baseline, or a significant positive correlation after muDX400 treatment with the percentage of tumor-infiltrating CD45 + cells or CD3 + T cells at baseline ( Fig. 3C ; CD45 + cells: Pearson correlation = 0.84, P = 0.0013; T cells: Pearson correlation = 0.66, P = 0.026).

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