PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index.

Mol Cancer Ther · 2022 · PMC9377749 · PMID 35149549

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a positive trendno p-value reported

Indeed, although all THOP1-expressing models were responsive to PhAc-ALGP-Dox, potency nor efficacy correlates with THOP1 expression per se , although a positive trend towards maximal efficacy could be observed in vitro .

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