Pan-cancer landscape of T-cell exhaustion heterogeneity within the tumor microenvironment revealed a progressive roadmap of hierarchical dysfunction associated with prognosis and therapeutic efficacy.

EBioMedicine · 2022 · PMC9382263 · PMID 35961204

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a decreasing trendno p-value reported

18 In the present study, we observed significant differences in the expression pattern of TCF1 and T-bet with a decreasing trend among the five TEX subgroups and TOX with a decreasing trend from TEX C1 to C4 but highest in C5 ( Figure 1 c).

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