LINE-1 and Alu methylation signatures in autism spectrum disorder and their associations with the expression of autism-related genes.

Sci Rep · 2022 · PMC9385849 · PMID 35978033

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highly significantno p-value reported

According to a recent study using blood samples from ASD, one of CpG sites within the LINE-1 sequence showed a slight decrease of methylation levels in ASD compared to unaffected controls but its methylation level was highly significant in ASD with mental regression 28 .

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