Four of the subcongenic strains, excluding Pr1.103, showed lower levels of Kim-1 expression either at a significant or marginally significant level when compared with SHRSP ( Fig. 3B ), implying that they were more resistant to salt-induced renal tubular damage.
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A 3-Mbp fragment on rat chromosome 1 affects susceptibility both to stroke and kidney injury under salt loading in the stroke-prone spontaneously hypertensive rat: a genetic approach using multiple congenic strains.
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