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Rapid evaluation of COVID-19 vaccine effectiveness against symptomatic infection with SARS-CoV-2 variants by analysis of genetic distance.

Nat Med · 2022 · PMC9388371 · PMID 35710987

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a decreasing trendno p-value reported
In general, a decreasing trend of VE is depicted, with a sharp drop after the Omicron predominance since December 2021.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.