Elevated serum CEA is associated with liver metastasis and distinctive circulating tumor DNA alterations in patients with castration-resistant prostate cancer.

Laboratory progression was defined as a rise in prostate‐specific antigen (PSA) of >2 ng/ml and >25% from treatment nadir with a second subsequent PSA confirming a positive trend, or alternatively as a change in therapy due to rising PSA if this occurred before the above.

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