Barely Significant
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Phase I safety and immunogenicity study of a Brazilian serogroup B vaccine.

Braz J Infect Dis · 2021 · PMC9392203 · PMID 34793713

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an increasing trendno p-value reported
There was an increasing trend for local adverse events after larger doses, except for induration.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.