Connexin 30 deletion exacerbates cochlear senescence and age-related hearing loss.

We estimated the number of IHCs in cochlear specimens and found that Cx30 ΔΔ animals showed a decreasing trend in all cochlear turns, although the difference between Cx30 ΔΔ and Cx30 WT was not significant ( Figure 2H ), suggesting that aging could be the dominant factor determining IHC damage.

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