Meta-Analysis and Systematic Review of the Association between a Hypoactive <i>NCF1</i> Variant and Various Autoimmune Diseases.

Antioxidants (Basel) · 2022 · PMC9404811 · PMID 36009308

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hedged sentences

0.0000

closest p · 0.0× alpha

0.0540

boldest claim

The sentences

highly significantp < 1 × 10 −16actually significant

As expected, our meta-analysis confirmed a highly significant association between the GTF2I rs117026326 polymorphism and pSS (OR = 2.17; 95% CI = 2.00–2.34, p < 1 × 10 −16 ) ( Figure 4 A).

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marginally significantp = 0.054so close (0.05 < p ≤ 0.1)

The meta-analysis with the two studies revealed a marginally significant association of the GTF2I rs117026326 polymorphism with NMOSD (OR = 1.92; 95% CI = 0.99–3.73, p = 0.054) ( Figure 4 D).

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