FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.

DNA Promoter Methylation Was Responsible for the Downregulation of FAM107A Expression According to the analysis of the Smartapp database, multiple probes in the FAM107A promoter region showed higher β values in PCa tissues than in normal tissues and a decreasing trend of FAM107A expression with increasing β values ( Figure 3 A).

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