highly significantp = 0.0001
Indeed, although a highly significant association was observed between MSI and CD8+ TIL expression (27 MSI CRCs were CD8+ and 34 MSS cases showed CD8 negativity, p = 0.0001), 15 out of 43 MSI tumors (35%) were CD8- (MSI/CD8-) and 12 out of 46 MSS tumors (26%) were CD8+.