Prepubertal mammary glands from group HT-A expressed significantly higher Igf1 mRNA levels than both LT groups ( Figure 4 A), and there was a corresponding, highly significant, increase in Igf1 protein levels ( Figure 4 B).
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Early Dietary Exposures Epigenetically Program Mammary Cancer Susceptibility through Igf1-Mediated Expansion of the Mammary Stem Cell Compartment.
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