5-ALA Is a Potent Lactate Dehydrogenase Inhibitor but Not a Substrate: Implications for Cell Glycolysis and New Avenues in 5-ALA-Mediated Anticancer Action.

Cancers (Basel) · 2022 · PMC9406570 · PMID 36010996

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marginally significantno p-value reported

In fact, mitochondrial respiration-derived ATP showed a marginally significant increase in U87 cells upon the introduction of 5-ALA (~100 pmol/min) and in M059K cells upon introduction of TART (~75 pmol/min).

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