Food Reward Alterations during Obesity Are Associated with Inflammation in the Striatum in Mice: Beneficial Effects of <i>Akkermansia muciniphila</i>.

Cells · 2022 · PMC9406832 · PMID 36010611

Europe PMC DOI

hedged sentences

0.0058

closest p · 0.1× alpha

0.0440

boldest claim

The sentences

highly significantp = 0.0058actually significant

muciniphila showed a highly significant decrease in Lpl expression in the striatum as compared to placebo-treated obese mice ( p = 0.0058, Figure 4 C).

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an increasing trendp = 0.044actually significant

We detected significant increases in the expressions of Cd45 and Il1b and an increasing trend for Tnfa expression in obese mice as compared to lean mice ( p = 0.044, 0.025 and 0.052, respectively, DIO vs. lean mice, Figure 2 A), suggesting the induction of inflammation in the mesocorticolimbic area by HFD-induced obesity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Food Reward Alterations during Obesity Are Associated with Inflammation in the Striatum in Mice: Beneficial Effects of &lt;i&gt;Akkermansia muciniphila&lt;/i&gt;.

The sentences

Food Reward Alterations during Obesity Are Associated with Inflammation in the Striatum in Mice: Beneficial Effects of <i>Akkermansia muciniphila</i>.