highly significantp > 0.05
When comparing biliary specimens from patients with PSC-derived CCA and isolated PSC, miR-412, miR-640, miR-1537, and miR-3189 had a highly significant differentiating value [ 18 ]. miR-1537 in combination with CA19-9 resulted in higher diagnostic values than CA19-9 alone (AUC 0.91 versus 0.88; p > 0.05) [ 14 ].