Wnt/β-Catenin-Pathway Alterations and Homologous Recombination Deficiency in Cholangiocarcinoma Cell Lines and Clinical Samples: Towards Specific Vulnerabilities.

Here, a principal finding was the strong and highly significant upregulation of AXIN2 (10.9 log2 fold change, adj p = 3.71 × 10 −18 ; Table S4 ) in both mutated cell lines, which we verified by qRT-PCR and Western Blot analysis ( Figure 5 ).

also in 132,142 other papers