Genetic Variants in Epidermal Differentiation Complex Genes as Predictive Biomarkers for Atopic Eczema, Allergic Sensitization, and Eczema-Associated Asthma in a 6-Year Follow-Up Case-Control Study in Children.

We also observed a highly significant association between the FLG2 SNP with disease severity; a patient carrying at least one FLG2 rs12568784 allele [T] was approximately four times more likely of having moderate atopic dermatitis ( Table 3 A).

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