The result showed that cisplatin treatment had a slight trend to reduce the viability of F4/80 + macrophages in MTCQ-WT-formed tumors, and the effect was also noted in MTCQ mir21–/– -formed tumors ( online supplemental figure 6B ).
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Snail-regulated exosomal microRNA-21 suppresses NLRP3 inflammasome activity to enhance cisplatin resistance.
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