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Global, Regional, and National Trends of Chagas Disease from 1990 to 2019: Comprehensive Analysis of the Global Burden of Disease Study.

Glob Heart · 2022 · PMC9414802 · PMID 36051318

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a decreasing trendno p-value reported
During the year 2019, the global prevalence of CD was 6,469,283 (95% UI = 5,658,409.78–7,374,556.70), showing a decreasing trend compared to the prevalence reported in 1990.

also in 47,180 other papers

an increasing trendno p-value reported
Finally, the prevalence trends have followed different patterns according to the region, with a sustained decrease in Latin America, compared to an increasing trend in North America and Europe until 2010.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.