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Effectiveness of first-generation severe acute respiratory syndrome coronavirus 2 mRNA vaccines against the Omicron variant.

Clin Microbiol Infect · 2022 · PMC9420321 · PMID 36038121

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an evident trendno p-value reported
Despite this variability, there is an evident trend of reduced VE of mRNA vaccines, both primary series and boosters, against the Omicron variant (compared with that against previous variants), which further wanes over time.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.