Characterization of the SGLT2 Interaction Network and Its Regulation by SGLT2 Inhibitors: A Bioinformatic Analysis.

Front Pharmacol · 2022 · PMC9421436 · PMID 36046822

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Loss of its function in RIN-m cell line led to a highly significant increase in mRNA levels of the insulin regulator genes Ins1 and Ins2 leading to the activation of the glucose stimulated-insulin secretion (GSIS) pathway ( Alhaidan et al., 2021 ).

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