Effectiveness of CHIKV vaccine VLA1553 demonstrated by passive transfer of human sera.

JCI Insight · 2022 · PMC9431671 · PMID 35700051

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highly significantno p-value reported

When VLA1553 phase I serum of varying titers was transferred to NHPs prior to WT CHIKV challenge, animals showed a highly significant decrease of viral RNA of at least 3–5 logs, and transfer of the highest titer human sera resulted in a complete lack of CHIKV RNA detection.

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