Macrophage polarization regulates intervertebral disc degeneration by modulating cell proliferation, inflammation mediator secretion, and extracellular matrix metabolism.

Front Immunol · 2022 · PMC9433570 · PMID 36059551

Europe PMC DOI

hedged sentence

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

a decreasing trendP< 0.05actually significant

In contrast, collagen type Iα1 and MMP-13 an showed upregulated expression in the M1CM+ TNF-α-group, while the M2CM co-culture group showed a decreasing trend in this regard (all P< 0.05; Figures 3G, H ).

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.