It should also be noted that the highly significant p value for the digital biomarker differences in the COVID-19-negative group is likely attributable to the higher number of participants (9-fold higher) compared with the COVID-19-positive group.
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A method for intelligent allocation of diagnostic testing by leveraging data from commercial wearable devices: a case study on COVID-19.
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On average, daily RHR values more than two standard deviations from the baseline mean were present as early as 13 days prior to the positive test, with an increasing trend that peaked at 1 day prior to the test date (Fig. 1c , bottom).